Because the masks were put together by hand, it's possible that for one color in one position (Or more than one, I think Topps were possibly done in blocks) To be misaligned compared to the other colors.
What would be really hard would be proving that it was from that one plate being made a bit off instead of just being out of registration.
If you had an uncut sheet showing the color registered on most of the cards, but not on one or not on a block, AND a sheet showing the same cards all in register. That might be convincing.
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