From the airport, you take the Blue line to Addison, and there's a shuttle from the Addison Blue line to the ballpark.
From your hotel really depends on where you are staying. Are you in the Loop?
If so, take the Red line up and get off at Addison. Drops you off right in front of the park.
Of course, I would recommend against going there all together, but that's a conversation for a different day
