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Marc S.There was a grading company that did just that, although their name escapes me as of right now. I think it was CTA?
Bottom line is that the program was not sophisticated enough to pick up altering techniques. Just check out much of what Kevin Saucier has publically tough us here. The time and expense to properly write script and programs that would allow a machine to do such alterting is much higher than the cost of the human eye and borrowing some of its time.
Seriously, as someone who works for a company that has excellent Script writers, I don't know how you could realistically generate a program that identifies a re-backed card, for example, without causing damage/ruin to the card. And that is a somewhat simplistic alteration.