Now that I've wiped the drool from my face -
I prefer the ink to be consistent with the era. I owned 2 1966 Topps Curt Ford PSA/DNA cards at the same time. I sold the Sharpie and kept the ink for that very reason. It just looked more vintage. (Curt Flood sigs below, these all passed PSA/DNA)
Ball point pen on modern card (especially the glossy ones from the 90's and 2000's) really look bad in my opinion. The ink just doesn't take to them very well, therefore, Sharpie is the only way to go. (2001 Topps Traded Pujols Sharpie pic below)