In the E121-80 there aren't the high dollar cards like the T206 Wagner and the T205 Hoblitzel. You'll pay well for the Ruth(s), Cobb, Johnson, etc... However, there are certain cards in the E121-80 that just aren't seen and are much, much more difficult (in my opinion) than the rarer cards in the T206 or T205 sets. If you check both the SGC and PSA population reports there are some cards that may have less than 10 graded copies. Most of these consist of Giants and Yankees players. If you search back through the E121 threads there's one that tracks some of the scarcities. In the price guides these tougher cards are listed as "commons" but typically sell for much more than the easier group of cards.
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