[jchcollins]

It's a very personal decision. I would be on the side that says don't sell your favorite card if you don't have to, but then again I am in it much more for the cards than the money and I don't have anything in my collection worth even a fraction of that card. There are those who always intend to get rid of their cards at some point; if you are one of those types of collector / investors then it may well be worth considering peaks and where exactly the market is. But I would also use the "regret meter" - are you going to be kicking yourself a month from now if you sell it? I try to approach decisions kind of like that even if moving some of my smaller pieces around.