Yes, they've quintupled in price in the past year. Most hobby shops will only let you buy a pack or two, and that's with the purchase of a box.
Started last year with the shortage of semirigid sleeves (Cardsavers) with all the people submitting to PSA. Because of that, PSA started accepting cards in regular toploaders last summer, so those started getting hoarded.
Because of COVID, supply chain stuff for products coming from China is all screwed up, so it's hard to manufacture for the increased demand. Then with the March shipping fiasco in the Suez Canal, global shipping lines were delayed.
Stuff piling on stuff piling on more stuff. COMC will buy new/gently used toploaders from people for 10 cents each, but they're worth much more if you sell them straight on eBay. They're trying to track down additional suppliers, but most toploader cases are backordered or again, way too expensive to be throw-ins based on their profit margin.
Add: Just like the price of lumber, plastics are much higher now than previous. Went to lunch today and the owner was saying that to buy a case of plastic take-out containers would cost 5x last year's price, if they could even get them