I've knocked the top card off my want list a few times:
--I searched for an E282 (Oh Boy Gum; Goudey's 1st card product) Jack Dempsey for years before snagging one on Ebay a few years ago. Haven't seen another since.
--I found my #1 baseball card, a Pebble Beach Clothiers Lefty O'Doul, at the 2006 National.
--I got a signed 1951 Ringside Ray Miller in a Clean Sweep auction a few years ago.