I think the majority of the T206's were printed on large sheets just like the one you have assembled with your T220 panels. I say majority because I think it's possible that some smaller sheets were printed at other facility's with ties to ALC.
We have pretty solid evidence of the minimum width of the sheets with one of the plate scratch sheets that has 24 cards in a horizontal row.
I think they changed the layouts but kept the sheet size when that got to the the last two smaller print groups (3 and 4).
The backs these test print scraps show a minimum of 17 cards in a horizontal row and it could easily also be 24 if the "exclusive 12" were double printed horizontally to fit the sheet and that would explain why the two different Pfeffer's have different subjects on the backs.
Test Print Scrap - Copy.jpg