I have done the Topps run 1948 and 1951-2016. ( and Bowman 48-55) Up to 1994 I have also collected any test or insert sets listed for Topps in the SCD Standard Catalog ( up to 2011 it included post 1980 stuff, it no longer does). After 1994 the proliferation grew to great. So after that date I only did the base set and any update/traded set. I also have done all the Heritage sets and any updates to them. I keep all the traded/update sets with my base sets.
Some people include them, some don't. I think if you are an OCD collector you include them
....and of course you need all the cataloged variations to all the sets...and an unopened pack too
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Good luck on your run, Sam