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Go Back   Net54baseball.com Forums > Net54baseball Postwar Sportscard Forums > WaterCooler Talk- Off Topics

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  #1  
Old 06-09-2021, 02:09 PM
steve B steve B is offline
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It's funny how some people are "oh, don't trust the government"
But the number of things they trust the government to regulate the safety of is huge.

Do you grade your own beef?
Decide what things will make your car safe to drive?
Or what can be in paint?
Or how many bug parts are allowed in a pound of each sort of vegetable?

Just where do you find the time?

Last edited by steve B; 06-09-2021 at 02:09 PM. Reason: typo
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  #2  
Old 06-09-2021, 10:35 PM
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Quote:
Originally Posted by steve B View Post

Do you grade your own beef?
Of course not. It goes straight to PSA. I like to see if they notice it's been trimmed.
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  #3  
Old 06-10-2021, 06:28 AM
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https://youtu.be/l9EOc9SFCdg
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  #4  
Old 06-10-2021, 07:38 AM
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Moderna and Pfizer are using lipid nanoparticles that contain polyethylene glycol (PEG)2 for this purpose. The mRNA is wrapped in lipid nanoparticles (LNPs) that carry it to your cells, and the LNPs are “PEGylated” — that is, chemically attached to PEG molecules to increase stability.

This experimental mRNA gene therapy and its lipid nanoparticle-based delivery system have never been approved for use in a vaccine or drug. This includes Pfizer’s and Moderna’s COVID-19 vaccines, which were only “authorized” for emergency use by the U.S. Food and Drug Administration — not “approved.”

Significant concerns have been raised over the technology, including the lipid nanoparticles, and Moderna actually abandoned it in 2017 after studies revealed a high rate of adverse effects

[T]here can be no assurance that our LNPs will not have undesired effects. Our LNPs could contribute, in whole or in part, to one or more of the following: immune reactions, infusion reactions, complement reactions, opsonation reactions, antibody reactions . . . or reactions to the PEG from some lipids or PEG otherwise associated with the LNP. Certain aspects of our investigational medicines may induce immune reactions from either the mRNA or the lipid as well as adverse reactions within liver pathways or degradation of the mRNA or the LNP, any of which could lead to significant adverse events in one or more of our clinical trials.

https://sciencebasedmedicine.org/lip...o-antivaxxers/

https://pubmed.ncbi.nlm.nih.gov/24715289/

Superparamagnetic nanoparticle delivery of DNA vaccine
Fatin Nawwab Al-Deen 1, Cordelia Selomulya, Charles Ma, Ross L Coppel
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PMID: 24715289

DOI: 10.1007/978-1-4939-0410-5_12
Abstract
The efficiency of delivery of DNA vaccines is often relatively low compared to protein vaccines. The use of superparamagnetic iron oxide nanoparticles (SPIONs) to deliver genes via magnetofection shows promise in improving the efficiency of gene delivery both in vitro and in vivo. In particular, the duration for gene transfection especially for in vitro application can be significantly reduced by magnetofection compared to the time required to achieve high gene transfection with standard protocols. SPIONs that have been rendered stable in physiological conditions can be used as both therapeutic and diagnostic agents due to their unique magnetic characteristics. Valuable features of iron oxide nanoparticles in bioapplications include a tight control over their size distribution, magnetic properties of these particles, and the ability to carry particular biomolecules to specific targets. The internalization and half-life of the particles within the body depend upon the method of synthesis. Numerous synthesis methods have been used to produce magnetic nanoparticles for bioapplications with different sizes and surface charges. The most common method for synthesizing nanometer-sized magnetite Fe3O4 particles in solution is by chemical coprecipitation of iron salts. The coprecipitation method is an effective technique for preparing a stable aqueous dispersions of iron oxide nanoparticles. We describe the production of Fe3O4-based SPIONs with high magnetization values (70 emu/g) under 15 kOe of the applied magnetic field at room temperature, with 0.01 emu/g remanence via a coprecipitation method in the presence of trisodium citrate as a stabilizer. Naked SPIONs often lack sufficient stability, hydrophilicity, and the capacity to be functionalized. In order to overcome these limitations, polycationic polymer was anchored on the surface of freshly prepared SPIONs by a direct electrostatic attraction between the negatively charged SPIONs (due to the presence of carboxylic groups) and the positively charged polymer. Polyethylenimine was chosen to modify the surface of SPIONs to assist the delivery of plasmid DNA into mammalian cells due to the polymer's extensive buffering capacity through the "proton sponge" effect.
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Old 06-10-2021, 08:14 AM
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You should read the entire science based medicine piece you posted. It debunks the concern. The part in bold you posted is a quote from what Dr. Gorski goes on to debunk. Reminds me of younger lawyers who pull soundbites from cases based on Westlaw searches without actually reading the case.
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Last edited by Peter_Spaeth; 06-10-2021 at 08:29 AM.
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  #6  
Old 06-10-2021, 09:45 AM
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Quote:
Originally Posted by Peter_Spaeth View Post
You should read the entire science based medicine piece you posted. It debunks the concern. The part in bold you posted is a quote from what Dr. Gorski goes on to debunk. Reminds me of younger lawyers who pull soundbites from cases based on Westlaw searches without actually reading the case.
So, the opinion of a breast cancer surgeon, who has many other questionable opinions about medicine and the like, is to be taken as truthful, factual and therefore it's end of the story because he said so?
Just like some other response I heard sometime ago that the science is settled, you also believe this based on this one man's opinion?
Gotcha, Pete.

"At the same time the academics admit, almost in a puzzled fashion, that these “anti-maskers” do their investigations in a very scientific manner. “Indeed,” the paper claims, “anti-maskers often reveal themselves to be more sophisticated in their understanding of how scientific knowledge is socially constructed than their ideological adversaries, who espouse naïve realism about the ‘objective’ truth of public health data.”

The MIT academics go on to admit that those opposed to masks are not afraid to get down and dirty in looking at statistics, nor are they afraid to increasingly question the media and government authorities, a trait MIT researchers call “a weaponization of critical thinking.” Even more surprising is the revelation that anti-maskers’ “approach to the pandemic is grounded in a more scientific rigor, not less.”


https://www.intellectualtakeout.org/...ally-rigorous/
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  #7  
Old 06-10-2021, 10:00 AM
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Quote:
Originally Posted by irv View Post
So, the opinion of a breast cancer surgeon, who has many other questionable opinions about medicine and the like, is to be taken as truthful, factual and therefore it's end of the story because he said so?
Just like some other response I heard sometime ago that the science is settled, you also believe this based on this one man's opinion?
Gotcha, Pete.

"At the same time the academics admit, almost in a puzzled fashion, that these “anti-maskers” do their investigations in a very scientific manner. “Indeed,” the paper claims, “anti-maskers often reveal themselves to be more sophisticated in their understanding of how scientific knowledge is socially constructed than their ideological adversaries, who espouse naïve realism about the ‘objective’ truth of public health data.”

The MIT academics go on to admit that those opposed to masks are not afraid to get down and dirty in looking at statistics, nor are they afraid to increasingly question the media and government authorities, a trait MIT researchers call “a weaponization of critical thinking.” Even more surprising is the revelation that anti-maskers’ “approach to the pandemic is grounded in a more scientific rigor, not less.”


https://www.intellectualtakeout.org/...ally-rigorous/
Nice deflection Dale. You didn't read the article and cut and pasted an excerpt thinking it supported your point of view. Instead of admitting it, you pivot to your favorite tactic, the straw man. Where did I ever say I took Dr. Gorski as gospel? My point was that the article doesn't support your point of view.

And funny how when you thought Dr. Gorski was supporting your point of view YOU had no issue quoting him despite that he was a breast cancer surgeon. LOL. In fact, you were quoting Joseph Mercola, an extremely controversial alternative medicine osteopath who makes a fortune selling supplements.
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Last edited by Peter_Spaeth; 06-10-2021 at 10:11 AM.
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